Rasburicase in the management of tumor lysis: an evidence-based review of its place in therapy
نویسندگان
چکیده
منابع مشابه
Rasburicase in the management of tumor lysis: an evidence-based review of its place in therapy
Tumor lysis syndrome (TLS) is a potentially life-threatening complication of cancer therapy characterized by two or more of the following laboratory abnormalities: hyperuricemia, hyperkalemia, hypocalcemia, and hyperphosphatemia, with resultant end-organ damage, eg, renal failure, seizures, or cardiac arrhythmias. High-risk patients include those with highly proliferative cancers and/or large t...
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15 صفحه اولThe Efficacy of Single Dose Rasburicase in Prevention or Treatment of Tumor Lysis Syndrome in Children
Background: Tumor lysis syndrome (TLS) is a major metabolic complication in patients with malignancy after initiation of chemotherapy or spontaneously without treatment. The role of Rasburicase (a recombinant urate-oxidase enzyme) in prevention and treatment of TLS has been demonstrated in recent years. We aimed to investigate the efficacy of a single dose of rasburicase in reducing the risk of...
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ژورنال
عنوان ژورنال: Core Evidence
سال: 2015
ISSN: 1555-175X
DOI: 10.2147/ce.s54995